The Official Marijuana & Hash Appreciation Thread [2.Dro]

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northside7;4504216 said:
How does one go about making hash oil?
there's a ton of tutorials on youtube.. it really just depends on what method you're comfortable with.. there's super safe ways & then there's methods by which you can kill yourself while attempting if you're not careful.
 
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I wonder what weed without the slight memory problems would feel like....anyone averse to a strain with this attribute?

Marijuana's negative effects on memory are well known. But now scientists have pinpointed where in the brain the drug causes this forgetfulness, and it's separate from where pot exerts its medicinal effects.

If this finding, drawn from experiments with lab mice, is also found to apply to humans, it means scientists someday may be able to design medical marijuana that doesn't impede a patient's working memory while treating his or her pain. Working memory is the ability to hold more than one thought in your head for a period of time.

"We have found that the starting point for this phenomenon — the effect of marijuana on working memory — is the astroglial cells," study researcher Giovanni Marsicano, of the French biomedical researcher institution INSERM, said in a statement.

Brain cells

The researchers found that this disruption of working memory comes not from the drug's effects directly on the brain's neurons, but on a different type of cells: the brain's helper cells called astroglia. (They are also called astrocytes, neuroglia or glial cells.)

The researchers studied how the mice reacted to marijuana's active component and several similar synthetic chemicals. They were looking specifically at the receptor on the brain cells that reacts to these chemicals called cannabinoids, which are compounds similar to the active components of marijuana, Tetrahydrocannabinol (THC). Such receptors exist on both neurons and astroglia.

They genetically engineered mice without these receptors on certain cells. One set of mice had no cannabinoid receptors in the brain; one set had the receptors only on neurons; and one set had the receptors only on the astroglia.

Marijuana mind

The mice learned to navigate a maze, then were tested in their ability to remember how after receiving a dose of THC or other cannabinoid. The two sets of mice with cannibinoid receptors on their astroglia had problems remembering directions. Those mice with the receptors only on their neurons completed the maze just fine, suggesting the THC wasn't affecting memory via the brain's neurons but rather through the astroglia.

They also looked at these astroglial cells in brain slices from the hippocampus (the brain area that deals with memory formation). After treatment with cannabinoids the astroglia released compounds that tamper with the signals sent between neurons, which may be how they cause marijuana-induced forgetfulness.

Marijuana's other effects — which have been found beneficial in the treatment of pain, seizures and other ailments — happen through the neurons. If cannabinoids can be designed to target just neurons, they might not have the negative effects on working memory currently seen in medical marijuana.

The study was published on March 1 in the journal Cell.

mnn.com/health/fitness-well-being/stories/future-rx-marijuana-without-the-forgetfulness

 
Israeli scientists have cultivated a cannabis plant that doesn’t get people stoned in a development that may help those smoking marijuana for medical purposes, a newspaper said on Wednesday.

According to the Maariv daily, the new cannabis looks, smells and even tastes the same, but does not induce any of the feelings normally associated with smoking marijuana that are brought on by the substance THC, or tetrahydrocannabinol.

“It has the same scent, shape and taste as the original plant — it’s all the same — but the numbing sensation that users are accustomed to has disappeared,” said Tzahi Klein, head of development at Tikkun Olam, the firm that developed the species.

“Many of our patients who tried the new plant come back to us and say: ‘You tricked me,’” because they assumed they had been given a placebo, he said.

According to Maariv, Tikkun Olam sought to neutralise the effect of the THC and to increase the effect of another substance called CBD, or cannabidiol, which has been shown to help diabetics and to ease various psychiatric disorders.

Not only does it leave users stone-cold sober, it also doesn’t induce the munchies, the hunger pangs that the drug’s smokers generally suffer.

Despite the innovation, it is unlikely to have any impact on Israeli law, which outlaws the use of marijuana as illegal except for medical purposes.

According to figures published earlier this year by Sheba Medical Centre and the Israel Cancer Association, medical marijuana has been approved for use by about 6,000 Israelis suffering from various illnesses.

rawstory.com/rs/2012/06/01/israeli-scientists-develop-marijuana-strain-without-the-high/
 
I ain't smoking no synthetic, man-made faux weed. I prefer my shit to be grown naturally, with the aid of talented growers, or as I refer to them herbologists. thats as much human involvement as I want and am comfortable with.....in other words leave my weed alone.
 
dispensary run this is what i had today and will tomorrow

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some purple cheese: meh ok high didnt last long

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some skywalker: solid as always nice high makes you nice and sleepy
 
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@terbear for you to hit up a dispensary do you need some sort of medical marijuana card?

I wish I had a link on a doctor here that could set me up with one, I used to have this link, a female, that would get it from the dispensary shit had my head in the clouds off of one puff
 
Hello everyone I've got a question, please disregard how much the opening of this post made me seem like a cop. But after you pinch the top of a plant what should you do to help cushion the shock. Water it for a few days straight? Or fertilize it? Or what.
 
El Payaso;4520476 said:
Hello everyone I've got a question, please disregard how much the opening of this post made me seem like a cop. But after you pinch the top of a plant what should you do to help cushion the shock. Water it for a few days straight? Or fertilize it? Or what.
Shock makes things like light intake /nutrient uptake slow a bit just like when you repot a plant so pinch right after watering it & let it ride a day or two under less harsh light & that should help it through the shock & get you back on the road pretty quick.

 
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tomorrow i'm going get the homie her card its about to be a smoke house in house... you get a free gram for first time patients, then you get another free gram for refering a friend, (some places match whatever you your buddy buys) plus what you buy so ima buy a 8th get 4.5 gram (8th is 3.5) but all the places that ive looked up do 4.5+1+1 and a edible going to a bunch of new dispensarys tomorrow so that i get my first time patient free gram so itll be another gram for me not just the basis of refer a friend. 7.5 grams of top shelf for 45 ima do it at mutiple places then go to a hash bar in hollywood.. like starbucks but you get to just smoke inside
 
@terbear I need to move to California.... They real tight with the medical marijuana cards here the dispensaries here got some fire though, best master kush I ever had was from the dispensary

I picked up a QP yesterday of some crazy trees, I'll post a pic of a bud later tonite.... Doing the fathers day thing at the moment
 
Desi_416;4533516 said:
@terbear I need to move to California.... They real tight with the medical marijuana cards here the dispensaries here got some fire though, best master kush I ever had was from the dispensary

I picked up a QP yesterday of some crazy trees, I'll post a pic of a bud later tonite.... Doing the fathers day thing at the moment

Shit pisses me off. I'm willing to drop $300 but these doctors are too full of themselves..

 
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couple pics of the Purple Diesel (at least thats what I think it is after some tedious research) that found its way into my lap, got a QP of it last night too, the pics arent the best quality, think the lighting was a little fucked, I'll try to post some more a little later.

Its my first time with Purple Diesel, I love it, minimal burnout, real nice high, makes u feel almost euphoric, its probably one of the best strains I've had when it comes to calming stress, doesn't really give you the munchies either which I'm thankful for.

 
northside7;4560692 said:
Desi_416;4533516 said:
@terbear I need to move to California.... They real tight with the medical marijuana cards here the dispensaries here got some fire though, best master kush I ever had was from the dispensary

I picked up a QP yesterday of some crazy trees, I'll post a pic of a bud later tonite.... Doing the fathers day thing at the moment

Shit pisses me off. I'm willing to drop $300 but these doctors are too full of themselves..

I feel you homey I've asked around too, there's apparently some criminal lawyer who "helps" you out with the application process as well as refers you to a doctor for the medical side of things, don't know if he's still around, can't remember the name he's spoke a few times at Queen's park during the weed march, seen a documentary on medical marijuana and found out about him from there

where in Canada you at?

 

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